In retinopathy of prematurity (ROP), the demarcation line between the vascularized and avascular retina in stage 2 disease is characterized by:
- A A flat, white line at the junction of vascular and avascular retina
- B A ridge of tissue with height and width at the junction ✓
- C A ridge with extraretinal fibrovascular proliferation
- D Partial retinal detachment
Explanation
ROP stage 2 is defined as a ridge, meaning the demarcation line gains both height and width at the junction of vascular and avascular retina. Stage 1 is a flat white demarcation line. Stage 3 adds extraretinal neovascularization from the ridge. Stage 4 and 5 involve partial and total retinal detachment respectively. The distinction between line (stage 1) and ridge (stage 2) is a key staging feature examined in ROP classification.
Reference: International Classification of Retinopathy of Prematurity, cited in Kanski, 9th ed.
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Written and medically reviewed by the StethoPrep medical team.