A 2-year-old child presents with a large retinal tumor with subretinal seeding and vitreous seeding. According to the International Intraocular Retinoblastoma Classification (IIRC), this eye is classified as:
- A Group B
- B Group E ✓
- C Group D
- D Group C
Correct answer: B. Group E
Explanation
IIRC Group B includes eyes with diffuse subretinal or vitreous seeding. Group E is defined as no visual potential or presence of any two of: neovascular glaucoma, massive intraocular hemorrhage, aseptic orbital cellulitis, tumor anterior to vitreous base, tumor touching the lens, or diffuse infiltrating retinoblastoma. Group D is confined to retina with subretinal fluid <5 mm. Group C has localized seeding. The question describes diffuse seeding fitting Group B.
Reference: Shields' Retinoblastoma: Clinical Advances and Management, 1st ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.