Ophthalmology · Ocular Trauma and Emergencies (Chemical Burns, Open Globe, Endophthalmitis)

The Endophthalmitis Vitrectomy Study (EVS) found that immediate vitrectomy (compared to vitreous tap/biopsy) was superior in which specific clinical situation?

  • A All post-cataract endophthalmitis regardless of visual acuity
  • B Post-cataract endophthalmitis with presenting visual acuity of light perception only
  • C Post-cataract endophthalmitis with visual acuity of hand movements or better
  • D Post-cataract endophthalmitis in diabetic patients only
Correct answer: B. Post-cataract endophthalmitis with presenting visual acuity of light perception only

Explanation

The Endophthalmitis Vitrectomy Study (EVS) demonstrated that immediate pars plana vitrectomy provided superior visual outcomes compared to vitreous tap/biopsy only in patients presenting with light perception (LP) vision. In patients with hand movements (HM) or better vision, vitrectomy offered no additional benefit over tap/biopsy. The study also showed that systemic antibiotics did not improve outcomes in post-cataract surgery endophthalmitis. This remains a landmark benchmark for managing post-operative endophthalmitis.

Reference: Khurana Comprehensive Ophthalmology, 7th ed.

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