Ophthalmology · Ocular Trauma and Emergencies (Chemical Burns, Open Globe, Endophthalmitis)

Roper-Hall classification of chemical eye injuries grades severity. A Grade III injury is characterized by:

  • A Minimal conjunctival ischemia, corneal epithelial erosion only — good prognosis
  • B Corneal haze but iris details visible, limbal ischemia involving one-third to one-half of limbus — guarded prognosis
  • C Total corneal haze obscuring iris details, total limbal ischemia — very poor prognosis
  • D Ischemia of one-third or less of limbus, stromal haze with iris details visible — good prognosis
Correct answer: B. Corneal haze but iris details visible, limbal ischemia involving one-third to one-half of limbus — guarded prognosis

Explanation

The Roper-Hall (modified Hughes) classification grades chemical injury from I to IV. Grade III: corneal epithelial loss + stromal haze (iris obscured), limbal ischemia 1/3 to 1/2 of limbal circumference — GUARDED prognosis. Grade I: epithelial damage only, no ischemia — GOOD prognosis. Grade II: corneal haze with iris visible, ischemia <1/3 limbus — GOOD prognosis. Grade IV: opaque cornea with iris/pupil completely obscured, >1/2 limbal ischemia — VERY POOR prognosis. Grade III and IV are at risk for permanent visual impairment, limbal stem cell deficiency, and symblepharon.

Reference: Khurana Comprehensive Ophthalmology, 7th ed.

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