In the Endophthalmitis Vitrectomy Study (EVS), immediate pars plana vitrectomy (compared to vitreous tap/biopsy alone) showed a significant visual benefit in patients with endophthalmitis who presented with:

• A Hand motion (HM) or better vision at presentation
• B All patients regardless of initial vision
• C Those with corneal edema and hypopyon
• D Light perception (LP) or worse vision at presentation ✓

Explanation

The Endophthalmitis Vitrectomy Study (EVS) showed that immediate PPV produced significantly better visual outcomes compared to vitreous tap/biopsy only in patients presenting with light perception (LP) vision or worse. For patients with hand motion (HM) or better vision at presentation, immediate vitrectomy offered no significant benefit over tap/biopsy. This landmark finding guides the decision to perform PPV in post-cataract endophthalmitis based on presenting visual acuity.

Reference: Khurana Comprehensive Ophthalmology, 7th ed.

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Written and medically reviewed by the StethoPrep medical team.