Ophthalmology · Ocular Trauma and Emergencies (Chemical Burns, Open Globe, Endophthalmitis)

Post-cataract surgery endophthalmitis occurring within 6 weeks of surgery most commonly involves which organism?

  • A Streptococcus viridans
  • B Coagulase-negative Staphylococci (Staphylococcus epidermidis)
  • C Pseudomonas aeruginosa
  • D Bacillus cereus
Correct answer: B. Coagulase-negative Staphylococci (Staphylococcus epidermidis)

Explanation

Acute post-cataract endophthalmitis (within 6 weeks) is most commonly caused by coagulase-negative staphylococci (especially Staphylococcus epidermidis), which account for approximately 70% of cases in the Endophthalmitis Vitrectomy Study (EVS). These are commensal organisms introduced during the perioperative period. Streptococcus species cause more virulent acute disease. Bacillus cereus is associated with post-traumatic endophthalmitis. Delayed endophthalmitis (months–years, bleb-associated) is more commonly caused by Streptococcus and H. influenzae.

Reference: Khurana Comprehensive Ophthalmology, 7th ed.

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