A 60-year-old woman with Stage IVA cervical carcinoma (bladder mucosal involvement confirmed on cystoscopy) is being evaluated for treatment. Which statement is correct regarding her management?
- A Radical cystectomy with pelvic exenteration is the only curative option
- B Concurrent chemoradiation is the primary treatment ✓
- C Neoadjuvant chemotherapy followed by surgery is standard
- D Palliative chemotherapy alone is indicated
Correct answer: B. Concurrent chemoradiation is the primary treatment
Explanation
Stage IVA cervical cancer (bladder or rectal mucosa involvement or extension beyond the true pelvis) is treated with concurrent chemoradiation as primary therapy. Pelvic exenteration may be considered for selected patients with central pelvic disease after radiation but is not the standard first-line. Neoadjuvant chemotherapy is not standard for Stage IVA.
Reference: NCCN Guidelines: Cervical Cancer, 2024 ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.