A 24-year-old woman receives the nonavalent HPV vaccine at a public health clinic. Compared with the earlier quadrivalent vaccine, which additional high-risk HPV types does the nonavalent vaccine cover?
- A HPV 31, 33, 45, 52, 58 ✓
- B HPV 26, 53, 66, 68, 73
- C HPV 35, 39, 51, 56, 59
- D HPV 30, 34, 43, 44, 61
Correct answer: A. HPV 31, 33, 45, 52, 58
Explanation
The nonavalent (9-valent) vaccine contains L1 virus-like particles for types 6, 11, 16, 18 plus five additional oncogenic types: 31, 33, 45, 52 and 58, together accounting for roughly 90 percent of cervical cancers. The other lists contain real HPV genotypes but none are included in any licensed vaccine. Types 6 and 11 are retained for protection against genital warts.
Reference: Williams Gynecology, 4th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.