A 35-year-old pregnant woman at 12 weeks gestation is found to be rubella IgM-positive on routine screening. Her obstetrician is concerned about congenital rubella syndrome. Which of the following is NOT a feature of congenital rubella syndrome?
- A Patent ductus arteriosus
- B Hydrocephalus ✓
- C Cataracts
- D Sensorineural deafness
Correct answer: B. Hydrocephalus
Explanation
The classic triad of Congenital Rubella Syndrome (Gregg's triad) comprises cataracts, cardiac defects (especially patent ductus arteriosus and pulmonary artery stenosis), and sensorineural deafness. Hydrocephalus is not a recognised feature of CRS; it is associated with congenital toxoplasmosis and CMV infection. Microcephaly, hepatosplenomegaly, thrombocytopaenic purpura ('blueberry muffin' lesions), and retinopathy are additional features of CRS.
Reference: Ananthanarayan & Paniker's Textbook of Microbiology, 11th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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