ENT · Vertigo and Balance — Advanced (VEMP, Videonystagmography, Central vs Peripheral)

On cervical vestibular evoked myogenic potential testing, a patient shows a well-preserved P1-N1 amplitude but markedly prolonged P1 latency compared with age-matched norms. This pattern is most consistent with:

  • A Saccular end-organ hypofunction
  • B Cochlear outer hair cell dysfunction
  • C Conduction delay along the vestibular nerve or vestibulospinal pathway
  • D Excessive sternocleidomastoid tone during recording
Correct answer: C. Conduction delay along the vestibular nerve or vestibulospinal pathway

Explanation

cVEMP normative latencies are roughly P1 near 13 milliseconds and N1 near 23 milliseconds. Reduced amplitude with normal latency suggests end-organ (saccular) hypofunction, while delayed latencies with preserved amplitude indicate slowed conduction, classically seen in retro-labyrinthine lesions such as vestibular schwannoma compressing the eighth nerve. Amplitude alone reflects myogenic response strength, so a preserved amplitude argues against severe end-organ loss.

Reference: Cummings Otolaryngology: Head and Neck Surgery, 7th ed.

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