Which statement about sinonasal inverted papilloma is correct?
- A It most commonly arises from the nasal septum
- B It is associated with synchronous or metachronous squamous cell carcinoma in roughly 5 to 15 percent of cases ✓
- C Recurrence after excision is rare, under 5 percent
- D It characteristically arises from the floor of the nasal cavity
Correct answer: B. It is associated with synchronous or metachronous squamous cell carcinoma in roughly 5 to 15 percent of cases
Explanation
Inverted papilloma is a Schneiderian papilloma arising most often from the lateral nasal wall in the middle meatus, and it carries a genuine risk of malignant transformation to squamous cell carcinoma in approximately 5 to 15 percent of cases, justifying complete resection with long-term follow-up. Recurrence rates after incomplete excision are high, historically around 20 percent or more. Septal origin describes fungiform papilloma, the other Schneiderian subtype.
Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.