ENT · Rhinitis, Nasal Septal Disorders and Congenital Anomalies

A 28-year-old woman has perennial sneezing, watery rhinorrhoea and nasal itching with negative skin prick tests and normal total IgE. Nasal cytology shows marked eosinophilia. Which diagnosis fits best?

  • A Vasomotor rhinitis
  • B Rhinitis medicamentosa
  • C Atrophic rhinitis
  • D Non-allergic rhinitis with eosinophilia syndrome (NARES)
Correct answer: D. Non-allergic rhinitis with eosinophilia syndrome (NARES)

Explanation

NARES presents with perennial allergic-type symptoms, absent atopy on testing, and prominent eosinophils on nasal smear. Patients often respond well to intranasal corticosteroids and have a tendency toward aspirin sensitivity and polyposis. Vasomotor rhinitis shows neutrophils or no eosinophilia on cytology, which is precisely the feature that separates it from NARES here.

Reference: Scott-Brown's Essential Otorhinolaryngology, 2nd ed.

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