A 25-year-old man presents with a history of recurrent epistaxis since childhood. Examination reveals multiple telangiectasias on the lips, tongue, and nasopharynx. The most likely diagnosis is:
- A Hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu disease) ✓
- B Juvenile nasopharyngeal angiofibroma
- C Nasopharyngeal carcinoma
- D Wegener's granulomatosis
Correct answer: A. Hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu disease)
Explanation
Hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu disease) is characterized by recurrent epistaxis, multiple telangiectasias on the skin and mucous membranes (lips, tongue, nasopharynx), and autosomal dominant inheritance. JNA presents in adolescent males with a vascular mass, not diffuse telangiectasias. NPC presents in older adults with cervical lymphadenopathy. Wegener's granulomatosis presents with lung and kidney involvement, not isolated telangiectasias.
Reference: Diseases of Ear, Nose and Throat, 7th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.