Juvenile nasopharyngeal angiofibroma (JNA) is characterised by all of the following EXCEPT:

• A Exclusive occurrence in adolescent males
• B Highly vascular tumour arising from the sphenopalatine foramen region
• C High rate of spontaneous malignant transformation requiring prophylactic radiation ✓
• D Mandatory preoperative embolisation followed by surgical excision

Explanation

JNA is a benign, highly vascular fibrovascular tumour occurring almost exclusively in adolescent males; it originates near the sphenopalatine foramen. It is treated by preoperative embolisation (to reduce intraoperative haemorrhage) followed by surgical excision (endoscopic or open). It does NOT undergo malignant transformation; radiation is not used prophylactically. Radiotherapy is reserved for unresectable intracranial extension. The statement about malignant transformation is false.

Reference: Dhingra Diseases of Ear, Nose and Throat, 7th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.