An inverted papilloma of the nose is distinct from benign nasal polyps in several ways. The most clinically important feature that mandates complete surgical excision (rather than polypectomy) is:

• A Its tendency to cause profuse epistaxis due to high vascularity
• B Its bilateral nature requiring bilateral FESS
• C Association with Samter's triad and aspirin sensitivity
• D High recurrence rate after simple polypectomy and malignant transformation potential (5–10% synchronous or metachronous SCC) ✓

Explanation

Inverted papilloma (Schneiderian papilloma) has two major clinically important features: a high recurrence rate after inadequate excision (requiring complete endoscopic or open resection with drilling of underlying bone) and an associated risk of squamous cell carcinoma either synchronously (~5–10%) or metachronously. These features mandate thorough preoperative MRI, complete surgical excision, and long-term endoscopic surveillance. It is not associated with Samter's triad.

Reference: Dhingra Diseases of Ear, Nose and Throat, 7th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.