Juvenile recurrent respiratory papillomatosis (JRRP) is most commonly caused by which HPV type(s)?
- A HPV 16 and 18
- B HPV 6 and 11 ✓
- C HPV 31 and 33
- D HPV 1 and 2
Correct answer: B. HPV 6 and 11
Explanation
Juvenile (onset) RRP is caused by HPV 6 (low-grade, less aggressive) and HPV 11 (associated with more aggressive disease, higher rate of pulmonary spread, and malignant transformation). Both are low-risk HPV types. HPV 16 and 18 are high-risk oncogenic types responsible for laryngeal SCC and cervical cancer but not papillomatosis. HPV 1 and 2 cause cutaneous (plantar) warts.
Reference: Dhingra Diseases of Ear, Nose and Throat, 7th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.