A biopsy from a genital wart shows squamous epithelium with superficial cells having a perinuclear halo and wrinkled, raisin-like nuclei. What are these cells called?

• A Molluscum bodies
• B Donovan bodies
• C Multinucleated giant cells
• D Koilocytes ✓

Explanation

Koilocytes are squamous cells with perinuclear halos and wrinkled, raisin-like nuclei, characteristic of HPV infection. Molluscum bodies are eosinophilic cytoplasmic inclusions seen in molluscum contagiosum. Multinucleated giant cells are seen in herpes simplex and varicella-zoster infections. Donovan bodies are seen in granuloma inguinale, appearing as safety-pin shaped organisms within macrophages on Giemsa stain.

Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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