Dermatology · Sexually Transmitted Diseases (Syphilis, Gonorrhea, Genital Ulcers)

A 45-year-old man with tabes dorsalis is examined. The pupils are small, irregular, and do not constrict to light, but constrict normally during accommodation. This finding is called:

  • A Adie pupil
  • B Horner syndrome
  • C Argyll Robertson pupil
  • D Marcus Gunn pupil
Correct answer: C. Argyll Robertson pupil

Explanation

The Argyll Robertson pupil, classically described as 'accommodates but does not react', is a feature of neurosyphilis, especially tabes dorsalis. The lesion lies in the pretectal region affecting light reflex fibres while sparing accommodation fibres. Adie pupil is a large tonic pupil with light-near dissociation from ciliary ganglion damage, Horner syndrome features miosis with ptosis and anhidrosis, and Marcus Gunn pupil is a relative afferent pupillary defect seen in optic nerve disease.

Reference: Harrison's Principles of Internal Medicine, 21st ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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