For repigmentation in localized, stable vitiligo unresponsive to medical therapy, the most effective surgical technique that yields the best colour match is:

• A Split-thickness skin grafting
• B Melanocyte-keratinocyte transplantation procedure (MKTP) using non-cultured cell suspension ✓
• C Suction blister epidermal grafting
• D Mini punch grafting

Explanation

The MKTP (melanocyte-keratinocyte transplantation procedure) using non-cultured epidermal cell suspension provides the best colour match with excellent repigmentation outcomes over large surface areas. A thin shave biopsy from the donor site is processed into a single-cell suspension and applied to the dermabraded recipient vitiligo patch. It has advantages over punch grafting (cobblestone effect) and split-thickness grafts for large areas. Suction blister grafting is useful for small discrete lesions on flat surfaces.

Reference: Neena Khanna Illustrated Synopsis of Dermatology & STD, 6th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.