A 20-year-old man with vitiligo shows segmental distribution following a dermatomal pattern on his trunk, which appeared abruptly and stabilized within 2 years. Koebner's phenomenon is absent. Which type of vitiligo is this?
- A Segmental vitiligo ✓
- B Generalized vitiligo (non-segmental)
- C Acrofacial vitiligo
- D Universal vitiligo
Explanation
Segmental vitiligo is a distinct clinical subtype characterized by unilateral distribution along a Blaschko-line or dermatomal pattern, rapid onset followed by stabilization within 1-2 years, and lack of Koebner's phenomenon. Unlike non-segmental vitiligo, it has a lower association with autoimmune disorders and is thought to involve somatic mosaicism and abnormal neural mechanisms (catecholamine toxicity hypothesis). Segmental vitiligo responds better to melanocyte transplantation procedures than non-segmental type.
Reference: Neena Khanna Illustrated Synopsis of Dermatology & STD, 6th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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