A dermatologist treating segmental vitiligo recommends melanocyte-keratinocyte transplantation procedure (MKTP). This surgical technique is best suited when:
- A Disease is actively spreading
- B Patient has Koebner phenomenon actively
- C Patient is on systemic steroids
- D Disease is stable for at least 6 months with less than 30% body surface area involvement ✓
Explanation
Surgical therapies for vitiligo (MKTP, suction blister grafting, split-thickness grafting) require disease stability — minimum 6 months (preferably 1 year) with no new lesions or Koebner phenomenon. BSA less than 30% is preferred for most techniques. MKTP (involves harvesting melanocytes and keratinocytes from donor skin, then applying as suspension to dermabrated recipient site) gives excellent cosmetic results in stable, limited vitiligo. Active disease is a contraindication to surgical treatment.
Reference: Neena Khanna Illustrated Synopsis of Dermatology & STD, 6th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.