Screening for which viral infection is recommended in all patients diagnosed with lichen planus, particularly those with erosive mucosal disease?

• A Hepatitis B virus
• B Epstein-Barr virus
• C Hepatitis C virus ✓
• D Human papillomavirus

Explanation

Lichen planus has a well-established association with hepatitis B virus infection, reported across multiple populations worldwide, and testing for HCV is advised especially in patients with erosive or ulcerative oral lichen planus. The proposed mechanism involves molecular mimicry between viral antigens and basal keratinocyte antigens. Hepatitis C, EBV, and HPV have no comparable established link with lichen planus, although HPV is discussed separately in vulvar and oral squamous carcinogenesis.

Reference: Fitzpatrick's Dermatology, 9th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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