Oral lichen planus has malignant potential. The variant with HIGHEST risk of malignant transformation is:

• A Reticular oral lichen planus (Wickham striae)
• B Plaque-type oral lichen planus
• C Papular oral lichen planus
• D Erosive/atrophic oral lichen planus ✓

Explanation

Erosive (atrophic/ulcerative) oral lichen planus carries the highest malignant transformation risk among OLP subtypes, estimated at approximately 1–2% over 5 years. The chronic mucosal erosion, associated dyskeratosis, and persistent inflammation in this variant predispose to squamous cell carcinoma. Reticular OLP (most common subtype with lacy white striae) has low malignant risk. Regular surveillance with biopsy of indurated or non-healing erosive areas is recommended. OLP is classified by the WHO as a 'potentially malignant disorder'.

Reference: Neena Khanna Illustrated Synopsis of Dermatology & STD, 6th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.