Dermatology · Papulosquamous Disorders (Psoriasis, Lichen Planus)

Histopathology of psoriasis shows regular elongation of rete ridges, thinning of suprapapillary plates, dilated tortuous capillaries in the dermal papillae, and collections of neutrophils. These neutrophilic collections within the stratum corneum are specifically called:

  • A Kogoj's spongiform pustules
  • B Pautrier's microabscesses
  • C Munro microabscesses
  • D Grenz zone infiltration
Correct answer: C. Munro microabscesses

Explanation

In psoriasis, there are two types of neutrophil collections: Munro microabscesses (collections within the parakeratotic stratum corneum) and Kogoj's spongiform pustules (neutrophils within the spinous and granular layers). Munro microabscesses are the hallmark of chronic plaque psoriasis histopathology. Kogoj's pustules are more prominent in pustular psoriasis. Pautrier's microabscesses are seen in mycosis fungoides (T-cells in the epidermis), not psoriasis.

Reference: Neena Khanna Illustrated Synopsis of Dermatology & STD, 6th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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