A borderline lepromatous (BL) patient on MDT develops upgrading (Type I reversal) reaction involving a facial nerve trunk with progressive foot drop. The minimal duration of corticosteroid therapy recommended by WHO to treat and prevent nerve function impairment in this reaction is:

• A 2 weeks
• B 3–6 months (WHO recommends a minimum of 12 weeks) ✓
• C 4 weeks
• D 6–12 weeks

Explanation

WHO guidelines recommend a minimum 12-week (3-month) course of corticosteroids (prednisolone starting at 40 mg/day with gradual taper) for Type I reversal reactions with nerve function impairment (NFI). This prolonged course is necessary because premature taper leads to rebound reactions and permanent nerve damage. The standard WHO steroid regimen for reactions with NFI extends to 12–24 weeks depending on clinical response. Shorter courses have higher rates of relapse and residual disability.

Reference: Neena Khanna Illustrated Synopsis of Dermatology & STD, 6th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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