Dermatology · Leprosy and Cutaneous Tuberculosis

A 28-year-old man from a leprosy-endemic area presents with a single hypopigmented, anaesthetic patch on his left forearm with loss of hair and anhidrosis over it. Skin smear from the lesion is negative. Slit-skin smear BI is 0. Which type of leprosy does he have?

  • A Tuberculoid leprosy (TT)
  • B Indeterminate leprosy
  • C Borderline tuberculoid (BT)
  • D Lepromatous leprosy (LL)
Correct answer: A. Tuberculoid leprosy (TT)

Explanation

A single well-defined hypopigmented anaesthetic patch with complete loss of appendages and a bacillary index of zero is characteristic of tuberculoid (TT) leprosy. In TT leprosy, the immune response is strong (Th1-dominant), resulting in complete nerve and adnexal destruction within the single lesion. Indeterminate leprosy has a poorly defined patch without definite nerve thickening, while BT has 2-4 lesions with partial sensation.

Reference: Neena Khanna Illustrated Synopsis of Dermatology & STD, 6th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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