Dermatology · Leprosy and Cutaneous Tuberculosis

Lupus vulgaris (LV) is the most common form of cutaneous tuberculosis in India. Its characteristic lesion is an 'apple-jelly' nodule seen on:

  • A Dermoscopy
  • B Wood's lamp examination
  • C Polarised light dermoscopy
  • D Diascopy (pressing a glass slide on the lesion)
Correct answer: D. Diascopy (pressing a glass slide on the lesion)

Explanation

The 'apple-jelly' sign of lupus vulgaris is demonstrated by diascopy: pressing a glass slide firmly against the brownish-red plaque blanches the overlying blood, revealing the underlying yellow-brown ('apple-jelly' coloured) granulomatous infiltrate. This translucent granulomatous colour is due to tuberculous granulomas in the dermis. Lupus vulgaris has a high tendency to relapse, scar, and undergo malignant transformation (SCC) in longstanding untreated lesions. It is a paucibacillary (high-immunity) form of cutaneous TB.

Reference: Neena Khanna Illustrated Synopsis of Dermatology & STD, 6th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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