A 40-year-old woman has scaly, crusted plaques over the malar region and seborrheic areas with a positive antinuclear antibody. Biopsy shows subcorneal acantholysis with interface change. Which eponym describes this entity?
- A Neumann type pemphigus vegetans
- B Hallopeau type pemphigus vegetans
- C Senear-Usher syndrome ✓
- D Gougerot-Carteaud syndrome
Correct answer: C. Senear-Usher syndrome
Explanation
Senear-Usher syndrome is pemphigus erythematosus, an overlap of pemphigus foliaceus and lupus erythematosus. It shows superficial subcorneal acantholysis, facial and seborrheic distribution, and frequent positivity for antinuclear antibody. Pemphigus vegetans presents as vegetating intertriginous plaques rather than malar scaly plaques, and Gougerot-Carteaud is confluent reticulated papillomatosis.
Reference: Rook's Textbook of Dermatology, 9th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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