Linear IgA bullous dermatosis (LABD) in adults most commonly presents with:

• A Nikolsky sign-positive flaccid blisters with oral erosions
• B Tense blisters on uninflamed skin in elderly
• C Grouped vesicles over extensor surfaces with intense pruritus
• D 'String of pearls' — vesicles arranged at the periphery of urticarial plaques ✓

Explanation

LABD classically shows the 'cluster of jewels' or 'string of pearls' pattern — new vesicles developing at the periphery of annular/urticarial plaques. DIF shows linear IgA at the BMZ, distinguishing it from DH (granular IgA) and BP (linear IgG/C3). The commonest drug trigger is vancomycin. In children (chronic bullous disease of childhood), lesions appear in a rosette pattern around the genitalia.

Reference: Neena Khanna Illustrated Synopsis of Dermatology & STD, 6th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.