In a patient with SJS/TEN overlap (15–30% BSA detachment) who is being transferred to a burn unit, which eye management is mandated from day 1 to prevent long-term sequelae?
- A Topical corticosteroid eye drops alone
- B Systemic antibiotic prophylaxis only
- C Aggressive ocular lubrication, lysis of symblepharon twice daily, and amniotic membrane transplant if severe ✓
- D Patching both eyes to prevent exposure keratopathy
Correct answer: C. Aggressive ocular lubrication, lysis of symblepharon twice daily, and amniotic membrane transplant if severe
Explanation
Ocular sequelae (symblepharon, dry eye, corneal scarring, blindness) are among the most devastating long-term complications of SJS/TEN, occurring in up to 40% of survivors. Early ophthalmology involvement is critical: aggressive lubrication, twice-daily mechanical lysis of symblepharon with a glass rod, and amniotic membrane transplantation (AMT) in severe cases are the standard of care to prevent adhesion formation and preserve vision. Patching increases the risk of synechiae formation.
Reference: Neena Khanna Illustrated Synopsis of Dermatology & STD, 6th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.