Dermatology · Cutaneous Manifestations of Systemic Disease (Diabetes, Internal Malignancy, Sarcoid)

Necrobiosis lipoidica diabeticorum (NLD) characteristically presents as:

  • A Bullae on dorsum of feet after minor trauma
  • B Discrete papules of xanthoma on Achilles tendon
  • C Yellowish-red plaques with central waxy atrophy and telangiectasias on the shins
  • D Pruritic hyperpigmented macules in flexures
Correct answer: C. Yellowish-red plaques with central waxy atrophy and telangiectasias on the shins

Explanation

Necrobiosis lipoidica diabeticorum presents as well-demarcated yellowish-red plaques with central waxy (porcelain-like) atrophy and prominent telangiectasias, classically on the pretibial area. Histologically it shows layered palisading granulomas with necrobiotic collagen. About 65% of cases occur in diabetics, but only ~0.3% of diabetics develop NLD. Bullosis diabeticorum is the non-scarring blistering disorder of diabetics; tendon xanthomata reflect familial hypercholesterolaemia.

Reference: Neena Khanna Illustrated Synopsis of Dermatology & STD, 6th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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