According to the manufacturer's recommendation, an opened vial of propofol infusion must be discarded after:

• A 48 hours
• B 24 hours
• C 12 hours
• D 6 hours ✓

Explanation

Propofol is presented as a lipid emulsion containing soybean oil, glycerol and egg phosphatide with no added preservative, and the formulation actively supports bacterial and fungal growth. Slow draw-up from a single vial over several hours has caused documented postoperative infection outbreaks. Hence strict asepsis at draw-up and disposal of any unused contents within 6 hours of opening are mandatory.

Reference: Morgan and Mikhail's Clinical Anesthesiology, 7th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.