What is the usual intravenous induction dose of propofol in a healthy unpremedicated young adult?

• A 0.3 mg/kg
• B 1 mg/kg
• C 2 mg/kg ✓
• D 4 mg/kg

Explanation

The standard induction dose of propofol in a healthy adult is approximately 1.5 to 2.5 mg/kg, conventionally quoted as 2 mg/kg. Children require a larger dose per kilogram because of a larger central compartment and faster clearance, whereas elderly and haemodynamically compromised patients need markedly less. Etomidate uses about 0.3 mg/kg and thiopentone 3 to 5 mg/kg, so option A reflects the wrong agent.

Reference: Morgan and Mikhail's Clinical Anesthesiology, 7th ed.

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