Embryology & Histology MCQs

Anatomy · 5 free questions with answers & explanations.

1. A newborn is noted to have a large meningomyelocele at the lumbosacral level, with neural tissue exposed and paraplegia below L3. This defect results from failure of which embryological process?
2. A 3-week-old infant presents with cyanosis that worsens with crying but improves with feeding (prone position). Examination shows choanal atresia. From which embryological structure does the choana normally develop?
3. On histological examination of the testis, a biopsy shows large cells with clear cytoplasm arranged in tubules, without spermatogenic cells, and only Sertoli cells are present. This 'Sertoli-cell-only' pattern suggests absence of which cell lineage?
4. A histology slide shows columnar cells with a brush border, arranged in a gland with a simple tubular structure opening into the lumen of the small intestine. The cells contain mucus-secreting granules. These are best identified as:
5. A 25-year-old woman undergoes a liver biopsy. The histology shows hepatocytes arranged in plates one cell thick, with sinusoids lined by fenestrated endothelium and a distinct perisinusoidal space (space of Disse). Vitamin A-storing fat cells are noted in this space. These fat-storing cells are called: