In negative pressure wound therapy (NPWT/VAC), the standard recommended pressure setting for most chronic wounds is:

• A -50 mmHg continuous
• B -200 mmHg continuous
• C -80 mmHg intermittent only
• D -125 mmHg continuous or intermittent ✓

Explanation

The standard pressure setting for VAC (vacuum-assisted closure) therapy is -125 mmHg, which may be applied continuously or in intermittent mode (5 minutes on, 2 minutes off). This pressure promotes granulation tissue formation, removes excess exudate, reduces oedema, and increases local blood flow. Lower pressures (-75 mmHg) may be used for sensitive/pain-limited wounds; higher pressures do not confer added benefit and may impair perfusion.

Reference: Bailey & Love's Short Practice of Surgery, 27th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.