Surgery · Thyroid and Parathyroid Surgery

The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) classifies FNA results into 6 categories. A Bethesda Category IV (Follicular Neoplasm/Suspicious for Follicular Neoplasm) carries an estimated risk of malignancy of approximately:

  • A 1–4%
  • B 50–75%
  • C 10–40%
  • D 95–99%
Correct answer: C. 10–40%

Explanation

TBSRTC Category IV (Follicular Neoplasm/Suspicious for Follicular Neoplasm) carries an implied risk of malignancy of 10–40% (updated TBSRTC 3rd edition 2023: ~25–40%). This category warrants diagnostic surgical excision (hemithyroidectomy or lobectomy) as FNA cannot distinguish follicular adenoma from follicular carcinoma, which requires histological demonstration of capsular/vascular invasion. Category VI (malignant) carries 97–99% malignancy risk.

Reference: Bailey & Love's Short Practice of Surgery, 27th ed.

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