Surgery · Thyroid and Parathyroid Surgery

In the Bethesda System for Reporting Thyroid Cytopathology (TBSRTC), a follicular neoplasm reported as Bethesda Category IV carries a malignancy risk of approximately:

  • A 1–4%
  • B 45–60%
  • C 10–40%
  • D More than 90%
Correct answer: C. 10–40%

Explanation

Bethesda Category IV (Follicular Neoplasm / Suspicious for Follicular Neoplasm) carries a malignancy risk of approximately 10–40% in the revised 2017 TBSRTC classification (reflecting the reclassification of non-invasive follicular thyroid neoplasm with papillary-like nuclear features [NIFTP]). The standard management is a diagnostic hemithyroidectomy to allow histological assessment of capsular/vascular invasion — which cannot be determined by FNA cytology alone.

Reference: Bailey & Love's Short Practice of Surgery, 27th ed.

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