A 35-year-old woman undergoes laparotomy for an ovarian mass. Histology shows ovary infiltrated by mucin-filled signet ring cells consistent with metastatic adenocarcinoma. Upper GI endoscopy reveals an ulceroproliferative growth in the stomach. What is the eponym for this ovarian metastasis from gastric carcinoma?
- A Sister Mary Joseph nodule
- B Krukenberg tumour ✓
- C Blumer shelf
- D Irish node
Correct answer: B. Krukenberg tumour
Explanation
Krukenberg tumour is ovarian metastasis of a mucin secreting signet ring cell carcinoma, most commonly from the stomach, spreading by transcoelomic or haematogenous routes. Sister Mary Joseph nodule is an umbilical metastasis, Blumer shelf is a rectovesical pouch deposit felt on digital rectal examination, and Irish node denotes left axillary nodal metastasis from abdominal malignancy. All four eponyms signal disseminated disease.
Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.