In Barrett's oesophagus surveillance, the Prague C&M classification records two measurements. 'C3 M6' indicates:

• A 3 cm of columnar mucosa with 6 goblet cells per high-power field
• B Circumferential segment 6 cm, with maximum extent 3 cm
• C 6 cm of intestinal metaplasia with 3 cm dysplastic segment
• D Circumferential Barrett's segment 3 cm long, with maximum extent 6 cm from GEJ ✓

Explanation

Prague C&M classification: C = length of the circumferential segment of Barrett's mucosa from the gastro-oesophageal junction; M = maximum extent including any tongue projections above the circumferential segment. C3 M6 means 3 cm of circumferential Barrett's with the furthest extent (tongue) reaching 6 cm above the GEJ. This standardised reporting replaced heterogeneous descriptive systems and enables reproducible audit of Barrett's surveillance programmes.

Reference: Bailey & Love's Short Practice of Surgery, 27th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.