Which tumor marker is most appropriate for post-treatment surveillance and monitoring for recurrence in a patient who has undergone curative resection for colorectal adenocarcinoma?
- A Carcinoembryonic antigen (CEA) ✓
- B CA 19-9
- C Alpha-fetoprotein (AFP)
- D CA 125
Correct answer: A. Carcinoembryonic antigen (CEA)
Explanation
CEA is the standard tumor marker for post-treatment surveillance of colorectal adenocarcinoma. Pre-operative CEA levels should be checked, and post-operative levels should be measured every 3-6 months for at least 3 years. B rising CEA prompts imaging to detect recurrence. CA 19-9 is used for pancreatic cancer, AFP for hepatocellular carcinoma, and CA 125 for ovarian cancer.
Reference: Harrison's Principles of Internal Medicine, 21st ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.