Which classification system grades the quality of the mesorectal excision specimen on pathological examination to predict oncological outcomes after rectal cancer surgery?
- A Dukes classification
- B Quirke grading (complete, near-complete, incomplete) ✓
- C Mandard tumour regression grade
- D Kikuchi classification
Correct answer: B. Quirke grading (complete, near-complete, incomplete)
Explanation
Quirke grading (also called the mesorectal grading system) assesses TME quality as complete (intact mesorectal envelope), near-complete (moderate bulk, minor defects), or incomplete (little mesorectum with positive/threatened CRM), correlating directly with local recurrence and survival. Mandard grades tumour regression after neoadjuvant therapy. Kikuchi grades submucosal invasion depth in early rectal cancers. Dukes stages by anatomical extent.
Reference: Bailey & Love's Short Practice of Surgery, 27th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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