A 45-year-old man with Lynch syndrome (MLH1 germline mutation confirmed) is diagnosed with a T2 N0 colon cancer in the splenic flexure. After completion of treatment, what is the recommended surveillance colonoscopy interval?
- A Every 1–2 years ✓
- B Every 5 years
- C Every 3 years
- D Once at 10 years post-resection
Correct answer: A. Every 1–2 years
Explanation
Lynch syndrome carries a lifetime colorectal cancer risk of up to 70% and a markedly elevated metachronous cancer risk. Current guidelines (ASCO, NICE, ESMO) recommend colonoscopic surveillance every 1–2 years for Lynch syndrome patients, in contrast to sporadic colorectal cancer where 3–5 yearly intervals are standard.
Reference: Bailey & Love's Short Practice of Surgery, 27th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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