The APPAC trial (Finland) assessed non-operative management with antibiotics versus appendicectomy for CT-confirmed uncomplicated acute appendicitis in adults. At 5-year follow-up, the recurrence (subsequent appendicectomy) rate in the antibiotics group was approximately:
- A 40% ✓
- B 10%
- C 25%
- D 55%
Correct answer: A. 40%
Explanation
The APPAC trial 5-year follow-up showed that approximately 39–41% of patients initially treated with antibiotics for uncomplicated appendicitis required appendicectomy within 5 years (cumulative recurrence). Importantly, no increased risk of perforation or complicated appendicitis was observed in those who eventually needed surgery. These data support antibiotics as a valid initial treatment option for selected patients, with about 60% avoiding surgery at 5 years.
Reference: Bailey & Love's Short Practice of Surgery, 27th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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