A 26-year-old woman develops spontaneous left leg swelling. CT venography shows compression of the left common iliac vein against the lumbar spine by the overlying right common iliac artery, with extensive left iliofemoral deep vein thrombosis. What is the diagnosis?

• A Paget-Schroetter syndrome
• B Klippel-Trenaunay syndrome
• C Budd-Chiari syndrome
• D May-Thurner syndrome (iliac vein compression syndrome) ✓

Explanation

May-Thurner syndrome is extrinsic compression of the left common iliac vein between the right common iliac artery anteriorly and the lumbar vertebra posteriorly, predisposing to left-sided iliofemoral DVT in young women. Paget-Schroetter is effort thrombosis of the subclavian vein, Budd-Chiari involves hepatic venous outflow obstruction, and Klippel-Trenaunay is a congenital vascular malformation triad. Treatment often includes catheter-directed thrombolysis plus stenting of the compressed segment.

Reference: Grainger and Allison's Diagnostic Radiology, 7th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.