In a pregnancy at 24 weeks, Doppler examination shows absent end-diastolic flow (AEDF) in the umbilical artery. This finding is associated with:
- A Uteroplacental insufficiency and increased fetal perinatal morbidity/mortality ✓
- B Macrosomia with polyhydramnios
- C Normal placental resistance in preterm pregnancy
- D Twin-to-twin transfusion syndrome exclusively
Correct answer: A. Uteroplacental insufficiency and increased fetal perinatal morbidity/mortality
Explanation
Absent end-diastolic flow in the umbilical artery indicates markedly elevated placental vascular resistance, reflecting uteroplacental insufficiency and fetal growth restriction. It is associated with perinatal mortality rates of up to 40% and mandates intensive surveillance or delivery depending on gestation. Reversed end-diastolic flow is even more severe. AEDF is not a normal finding at any gestation and is not specific to TTTS.
Reference: Grainger & Allison's Diagnostic Radiology, 7th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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