In FDG-PET/CT, the standardized uptake value (SUV) corrected for body weight is calculated as:

• A Tissue activity (MBq/mL) × body weight (g) / injected dose (MBq)
• B Injected dose (MBq) / tissue activity (MBq/mL) × body weight (kg)
• C Tissue activity (Bq/mL) / body surface area (m²) × injected dose (MBq)
• D Tissue activity (MBq/mL) / [injected dose (MBq) / body weight (g)] ✓

Explanation

SUV (body weight) = measured tissue radioactivity concentration (MBq/mL or kBq/mL) divided by injected activity normalized to body weight: [injected dose (MBq) / body weight (g)]. A SUV of 1.0 means the tissue activity equals what would be expected if the tracer distributed uniformly across all body tissues. SUVmax >2.5 is commonly used as a threshold for malignant FDG uptake. SUV calculations standardize quantification across patients and imaging centers, enabling treatment response assessment.

Reference: Grainger & Allison's Diagnostic Radiology, 7th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.