Radiology · Chest and Respiratory Radiology (Plain X-ray, CT, ILD, Pneumonia, Lung Cancer)

A 62-year-old smoker has a CT chest showing a spiculated peripheral lung mass with pleural tags and notching of the pleural surface. The most likely histological type is:

  • A Adenocarcinoma
  • B Squamous cell carcinoma
  • C Small cell carcinoma
  • D Large cell carcinoma
Correct answer: A. Adenocarcinoma

Explanation

Peripheral spiculated lesions with pleural tags are the classic CT presentation of pulmonary adenocarcinoma. Squamous cell carcinoma is typically central, arising from the main/lobar bronchi and often presenting as hilar mass or obstructive collapse. Small cell carcinoma presents as a central bulky hilar/mediastinal mass. Large cell carcinoma is a diagnosis of exclusion but tends to be large peripheral masses without the fine spiculation pattern.

Reference: Grainger & Allison's Diagnostic Radiology, 7th ed.

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