A 55-year-old woman with hoarding disorder has failed standard SSRI therapy. Which treatment approach has the strongest evidence for this condition?

• A High-dose venlafaxine
• B Specialized cognitive-behavioral therapy for hoarding ✓
• C Aripiprazole augmentation
• D Electroconvulsive therapy

Explanation

Specialized CBT targeting hoarding-specific cognitions and behaviors is the most evidence-based treatment for hoarding disorder, as standard SSRIs show limited efficacy. Venlafaxine has not shown specific benefit. Antipsychotic augmentation is not supported. ECT has no role in hoarding disorder treatment.

Reference: Diagnostic and Statistical Manual of Mental Disorders, 5th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.