In DSM-5, which of the following correctly distinguishes Mild Neurocognitive Disorder (NCD) from Major NCD?

• A In Mild NCD, cognitive decline does not interfere with independence in everyday activities; in Major NCD it does ✓
• B Mild NCD requires biomarker confirmation; Major NCD requires only clinical criteria
• C Mild NCD is always reversible; Major NCD is always progressive
• D Mild NCD affects only one cognitive domain; Major NCD affects ≥3 domains

Explanation

The key distinction between Mild and Major NCD in DSM-5 is functional impact: in Mild NCD, there is modest cognitive decline (reported by patient/informant or documented by testing) but cognitive deficits do NOT interfere with independence in everyday activities (complex IADL may require more effort or workarounds). In Major NCD (replaces 'dementia'), cognitive deficits significantly interfere with daily independence. Neither requires biomarker confirmation for diagnosis. Both can affect one or multiple cognitive domains. The reversibility/progression distinction does not define the categories.

Reference: Kaplan & Sadock's Synopsis of Psychiatry, 11th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.