Which intravenous induction agent is traditionally preferred for ECT because it has a rapid offset and the least tendency to raise the seizure threshold?

• A Propofol
• B Ketamine
• C Thiopentone
• D Methohexitone ✓

Explanation

Methohexitone, given at about 0.75 to 1 mg/kg, is the classical barbiturate of choice for ECT: it is ultra short acting and has minimal anticonvulsant properties, so it does not interfere with eliciting an adequate seizure. Thiopentone and propofol raise the seizure threshold and may require higher electrical stimuli, while ketamine increases postictal confusion and is not standard.

Reference: Kaplan and Sadock's Synopsis of Psychiatry, 11th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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